Lactobacillus reuteri ZJ617 Culture Supernatant Attenuates Acute Liver Injury Induced in Mice by Lipopolysaccharide

Lactobacillus rhamnosus GG culture supernatant (LGGs) promotes intestinal integrity and ameliorates acute liver injury induced by alcohol in mice. The aim of this study was to investigate the protective effects and molecular mechanisms of Lactobacillus reuteri ZJ617 culture supernatant (ZJ617s) on a...

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Veröffentlicht in:	The Journal of nutrition 2019-11, Vol.149 (11), p.2046-2055
Hauptverfasser:	Cui, Yanjun, Qi, Sirui, Zhang, Wenming, Mao, Jiangdi, Tang, Renlong, Wang, Chong, Liu, Jianxin, Luo, Xin M, Wang, Haifeng
Format:	Artikel
Sprache:	eng
Schlagworte:	Alanine Alanine transaminase Animals Apoptosis Aspartate transaminase Autophagy Biomarkers Body weight c-Jun protein Caspase-3 Chemical and Drug Induced Liver Injury - pathology Chemical and Drug Induced Liver Injury - physiopathology Chemical and Drug Induced Liver Injury - prevention & control Culture Media, Conditioned Dietary supplements Disease Models, Animal Extracellular signal-regulated kinase Inflammation Inflammation Mediators - blood Inflammation Mediators - metabolism Injection Injuries Inoculation Integrity Interleukin 10 Interleukin 6 Intestine JNK protein Kinases Lactobacillus reuteri Lactobacillus reuteri ZJ617 Lactobacillus rhamnosus Lactobacillus rhamnosus GG Limosilactobacillus reuteri Lipopolysaccharides Lipopolysaccharides - toxicity Liver Liver - drug effects Liver - metabolism Liver - pathology Liver diseases Male MAP kinase MAP Kinase Signaling System MAPK signaling Mice Mice, Inbred C57BL Microtubule-associated protein 1 Molecular modelling NF-kappa B - metabolism NF-κB protein Phagocytosis Phosphorylation Probiotics - pharmacology Protective Agents - pharmacology Protein kinase Proteins Rodents Signal Transduction Toll-Like Receptor 4 - metabolism Transcription factors
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