Novel protein vaccine candidates against Group B streptococcal infection identified using alkaline phosphatase fusions

Using an alkaline phosphatase-based genetic screening method, we identified a number of proteins that are potentially located on the outer surface of Group B streptococcus (Streptococcus agalactiae). In an enzyme-linked immunosorbent assay, antisera raised against two of the proteins, the streptococ...

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Veröffentlicht in:	FEMS microbiology letters 2003-05, Vol.222 (2), p.263-271
Hauptverfasser:	Hughes, Martin JG, Wilson, Rebecca, Moore, Joanne C, Lane, Jonathan D, Dobson, Richard J, Muckett, Phillip, Zabin Younes, Pribul, Philippa, Topping, Andrew, Feldman, Robert G, Santangelo, Joseph D
Format:	Artikel
Sprache:	eng
Schlagworte:	ABC transporter Alkaline phosphatase Antisera Enzyme-linked immunosorbent assay Genetic screening Homology Immunoglobulin G Microbiology Neonates Phosphatase Proteins Serotypes Streptococcus Streptococcus infections Vaccines
Online-Zugang:	Volltext
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