Ultrastructural Characteristics of HPV in Women's Vaginal Cells
Background/Objectives: This study examines the microstructural characteristics of HPV-infected koilocytes microscope taken from the smear test of women's vaginal cells and the shape of HPV particles under a light. Methods/Statistical analysis: Koilocytes infected with human papilloma virus were...
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Veröffentlicht in: | Research journal of pharmacy and technology 2019-09, Vol.12 (9), p.4305-4309 |
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description | Background/Objectives: This study examines the microstructural characteristics of HPV-infected koilocytes microscope taken from the smear test of women's vaginal cells and the shape of HPV particles under a light. Methods/Statistical analysis: Koilocytes infected with human papilloma virus were stained with Papanicolaou's method and examined by light microscopy. Ultrastructural characteristics of human papilloma virus inside the koilocyte were identified using transmission electron microscopy. Findings: The cytoplasm of a koilocyte infected with activated virus was filled with keratin filaments and some vacuoles and ribosomes. Activated HPV particles were clearly observed inside the nucleus. These virus particles were identified as spherical, with a diameter of 50 nm, and were mainly around nuclear membrane and nucleus. Improvements/Applications: This study identified that, as HPV invades and proliferates inside the nucleus of epithelial cells, the dysplasia of epithelial cells into koilocytes by forming a nucleophilic zone. |
doi_str_mv | 10.5958/0974-360X.2019.00740.6 |
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Methods/Statistical analysis: Koilocytes infected with human papilloma virus were stained with Papanicolaou's method and examined by light microscopy. Ultrastructural characteristics of human papilloma virus inside the koilocyte were identified using transmission electron microscopy. Findings: The cytoplasm of a koilocyte infected with activated virus was filled with keratin filaments and some vacuoles and ribosomes. Activated HPV particles were clearly observed inside the nucleus. These virus particles were identified as spherical, with a diameter of 50 nm, and were mainly around nuclear membrane and nucleus. Improvements/Applications: This study identified that, as HPV invades and proliferates inside the nucleus of epithelial cells, the dysplasia of epithelial cells into koilocytes by forming a nucleophilic zone.</description><identifier>ISSN: 0974-3618</identifier><identifier>EISSN: 0974-360X</identifier><identifier>EISSN: 0974-306X</identifier><identifier>DOI: 10.5958/0974-360X.2019.00740.6</identifier><language>eng</language><publisher>Raipur: A&V Publications</publisher><subject>Alcohol ; Cervical cancer ; Human papillomavirus ; Light ; Medical screening ; Morphology ; Nanotechnology ; Pathology ; Pharmaceuticals ; Transmission electron microscopy ; Tumors ; Virology ; Warts</subject><ispartof>Research journal of pharmacy and technology, 2019-09, Vol.12 (9), p.4305-4309</ispartof><rights>Copyright A&V Publications Sep 2019</rights><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c198t-7b940b79e16933dfcdfa3a763a40f9826cc9ac0e63db9cd26e0543980ee1c2803</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids></links><search><creatorcontrib>Park, Mi-Soon</creatorcontrib><creatorcontrib>Chang, Byung-Soo</creatorcontrib><title>Ultrastructural Characteristics of HPV in Women's Vaginal Cells</title><title>Research journal of pharmacy and technology</title><description>Background/Objectives: This study examines the microstructural characteristics of HPV-infected koilocytes microscope taken from the smear test of women's vaginal cells and the shape of HPV particles under a light. Methods/Statistical analysis: Koilocytes infected with human papilloma virus were stained with Papanicolaou's method and examined by light microscopy. Ultrastructural characteristics of human papilloma virus inside the koilocyte were identified using transmission electron microscopy. Findings: The cytoplasm of a koilocyte infected with activated virus was filled with keratin filaments and some vacuoles and ribosomes. Activated HPV particles were clearly observed inside the nucleus. These virus particles were identified as spherical, with a diameter of 50 nm, and were mainly around nuclear membrane and nucleus. Improvements/Applications: This study identified that, as HPV invades and proliferates inside the nucleus of epithelial cells, the dysplasia of epithelial cells into koilocytes by forming a nucleophilic zone.</description><subject>Alcohol</subject><subject>Cervical cancer</subject><subject>Human papillomavirus</subject><subject>Light</subject><subject>Medical screening</subject><subject>Morphology</subject><subject>Nanotechnology</subject><subject>Pathology</subject><subject>Pharmaceuticals</subject><subject>Transmission electron microscopy</subject><subject>Tumors</subject><subject>Virology</subject><subject>Warts</subject><issn>0974-3618</issn><issn>0974-360X</issn><issn>0974-306X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2019</creationdate><recordtype>article</recordtype><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><recordid>eNo9kF1LwzAUhoMoOOb-ghS88Kr1JGnzcSVSdBMGeuGmdyFNE-3o2pmkF_57Wyc7N-fA-_ByeBC6xpAVshB3IHmeUgYfGQEsMwCeQ8bO0OwUnJ9uLC7RIoQdjMNEQXIxQ_ebNnodoh9MHLxuk_JLe22i9U2IjQlJ75LV6zZpuuS939vuNiRb_dl0E2nbNlyhC6fbYBf_e442T49v5Spdvyyfy4d1arAUMeWVzKHi0mImKa2dqZ2mmjOqc3BSEGaM1AYso3UlTU2YhSKnUoC12BABdI5ujr0H338PNkS16wc_vhEUoTB2Eg7FSLEjZXwfgrdOHXyz1_5HYVCTLzWpUJMWNflSf74Uo7-sH10K</recordid><startdate>20190901</startdate><enddate>20190901</enddate><creator>Park, Mi-Soon</creator><creator>Chang, Byung-Soo</creator><general>A&V Publications</general><scope>AAYXX</scope><scope>CITATION</scope><scope>04Q</scope><scope>04S</scope><scope>04W</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>M0S</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope></search><sort><creationdate>20190901</creationdate><title>Ultrastructural Characteristics of HPV in Women's Vaginal Cells</title><author>Park, Mi-Soon ; Chang, Byung-Soo</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c198t-7b940b79e16933dfcdfa3a763a40f9826cc9ac0e63db9cd26e0543980ee1c2803</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2019</creationdate><topic>Alcohol</topic><topic>Cervical cancer</topic><topic>Human papillomavirus</topic><topic>Light</topic><topic>Medical screening</topic><topic>Morphology</topic><topic>Nanotechnology</topic><topic>Pathology</topic><topic>Pharmaceuticals</topic><topic>Transmission electron microscopy</topic><topic>Tumors</topic><topic>Virology</topic><topic>Warts</topic><toplevel>online_resources</toplevel><creatorcontrib>Park, Mi-Soon</creatorcontrib><creatorcontrib>Chang, Byung-Soo</creatorcontrib><collection>CrossRef</collection><collection>India Database</collection><collection>India Database: Business</collection><collection>India Database: Science & Technology</collection><collection>ProQuest Central (Corporate)</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><jtitle>Research journal of pharmacy and technology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Park, Mi-Soon</au><au>Chang, Byung-Soo</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Ultrastructural Characteristics of HPV in Women's Vaginal Cells</atitle><jtitle>Research journal of pharmacy and technology</jtitle><date>2019-09-01</date><risdate>2019</risdate><volume>12</volume><issue>9</issue><spage>4305</spage><epage>4309</epage><pages>4305-4309</pages><issn>0974-3618</issn><eissn>0974-360X</eissn><eissn>0974-306X</eissn><abstract>Background/Objectives: This study examines the microstructural characteristics of HPV-infected koilocytes microscope taken from the smear test of women's vaginal cells and the shape of HPV particles under a light. Methods/Statistical analysis: Koilocytes infected with human papilloma virus were stained with Papanicolaou's method and examined by light microscopy. Ultrastructural characteristics of human papilloma virus inside the koilocyte were identified using transmission electron microscopy. Findings: The cytoplasm of a koilocyte infected with activated virus was filled with keratin filaments and some vacuoles and ribosomes. Activated HPV particles were clearly observed inside the nucleus. These virus particles were identified as spherical, with a diameter of 50 nm, and were mainly around nuclear membrane and nucleus. Improvements/Applications: This study identified that, as HPV invades and proliferates inside the nucleus of epithelial cells, the dysplasia of epithelial cells into koilocytes by forming a nucleophilic zone.</abstract><cop>Raipur</cop><pub>A&V Publications</pub><doi>10.5958/0974-360X.2019.00740.6</doi><tpages>5</tpages></addata></record> |
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subjects | Alcohol Cervical cancer Human papillomavirus Light Medical screening Morphology Nanotechnology Pathology Pharmaceuticals Transmission electron microscopy Tumors Virology Warts |
title | Ultrastructural Characteristics of HPV in Women's Vaginal Cells |
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