Does the use of the combined oral contraceptive pill cause changes in the nasal physiology in young women?
Changes in nasal physiology have been observed during pregnancy and the menstrual cycle. The role of female hormones in these changes is unclear. The aim is to investigate the effect of the modern combined oral contraceptive pill (COCP). Eleven women were recruited from a family planning clinic. Ant...
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| Veröffentlicht in: | American journal of rhinology 2006-03, Vol.20 (2), p.238-240 |
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| creator | Wolstenholme, Charlotte R Philpott, Carl M Oloto, Emeka J Murty, George E |
| description | Changes in nasal physiology have been observed during pregnancy and the menstrual cycle. The role of female hormones in these changes is unclear. The aim is to investigate the effect of the modern combined oral contraceptive pill (COCP).
Eleven women were recruited from a family planning clinic. Anterior rhinoscopy, peak inspiratory flow rate, acoustic rhinometry, anterior rhinomanometry, mucociliary clearance time, and rhinitis quality-of-life questionnaire (RQLQ) scores were recorded at days 1 and 14 pre- and post-COCP.
Increased nasal obstruction midcycle pre-COCP, with significant differences for anterior rhinoscopy (p = 0.001) and peak inspiratory flow rate (p = 0.022), was found. No statistical difference was shown between pre- and post-COCP results apart from day 1 anterior rhinoscopy findings (p = 0.05).
The modern COCP has no significant effect on nasal physiology. |
| doi_str_mv | 10.1177/194589240602000225 |
| format | Article |
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Eleven women were recruited from a family planning clinic. Anterior rhinoscopy, peak inspiratory flow rate, acoustic rhinometry, anterior rhinomanometry, mucociliary clearance time, and rhinitis quality-of-life questionnaire (RQLQ) scores were recorded at days 1 and 14 pre- and post-COCP.
Increased nasal obstruction midcycle pre-COCP, with significant differences for anterior rhinoscopy (p = 0.001) and peak inspiratory flow rate (p = 0.022), was found. No statistical difference was shown between pre- and post-COCP results apart from day 1 anterior rhinoscopy findings (p = 0.05).
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Eleven women were recruited from a family planning clinic. Anterior rhinoscopy, peak inspiratory flow rate, acoustic rhinometry, anterior rhinomanometry, mucociliary clearance time, and rhinitis quality-of-life questionnaire (RQLQ) scores were recorded at days 1 and 14 pre- and post-COCP.
Increased nasal obstruction midcycle pre-COCP, with significant differences for anterior rhinoscopy (p = 0.001) and peak inspiratory flow rate (p = 0.022), was found. No statistical difference was shown between pre- and post-COCP results apart from day 1 anterior rhinoscopy findings (p = 0.05).
The modern COCP has no significant effect on nasal physiology.</description><subject>Administration, Intranasal</subject><subject>Adolescent</subject><subject>Adult</subject><subject>Airway Resistance - drug effects</subject><subject>Contraceptives, Oral, Combined - administration & dosage</subject><subject>Contraceptives, Oral, Combined - adverse effects</subject><subject>Female</subject><subject>Humans</subject><subject>Inspiratory Capacity - drug effects</subject><subject>Mucociliary Clearance - drug effects</subject><subject>Nasal Mucosa - physiopathology</subject><subject>Nasal Obstruction - chemically induced</subject><subject>Nose - drug effects</subject><subject>Nose - physiopathology</subject><subject>Pulmonary Ventilation - drug effects</subject><subject>Quality of Life</subject><subject>Rhinitis - chemically induced</subject><subject>Rhinomanometry</subject><subject>Rhinometry, Acoustic</subject><subject>Surveys and Questionnaires</subject><subject>Time Factors</subject><subject>Turbinates - physiopathology</subject><issn>1050-6586</issn><issn>1945-8924</issn><issn>1539-6290</issn><issn>1945-8932</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2006</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><recordid>eNplkEtPwzAQhC0EoqXwBzigiHvAj2TjnBAqT6kSFzhHtrNuUyVxiBNQ_j0urcSB086OvtmVhpBLRm8Yy7JbliepzHlCgXJKKefpEZmzVOQx8JweB01TGkMqYUbOvN9SyjIu2SmZMQAJIpdzsn1w6KNhg9HoMXL2VxrX6KrFMnK9qsPWDr0y2A3VF0ZdVQdL7WizUe06pKv2N9UqH-huM_nK1W497fzJje06-nYNtnfn5MSq2uPFYS7Ix9Pj-_IlXr09vy7vV7ERXA4xk9yA1UqCtZIrWQpEmmUlMOQigQQ1Q7AJCOAglM211qkodWJQogKjxYJc7-92vfsc0Q_F1o19G14WXFDJE2AQIL6HTO-879EWXV81qp8KRotdu8X_dkPo6nB51A2Wf5FDneIHiRt14w</recordid><startdate>20060301</startdate><enddate>20060301</enddate><creator>Wolstenholme, Charlotte R</creator><creator>Philpott, Carl M</creator><creator>Oloto, Emeka J</creator><creator>Murty, George E</creator><general>SAGE PUBLICATIONS, INC</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8AO</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>M0S</scope><scope>M1P</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope></search><sort><creationdate>20060301</creationdate><title>Does the use of the combined oral contraceptive pill cause changes in the nasal physiology in young women?</title><author>Wolstenholme, Charlotte R ; Philpott, Carl M ; Oloto, Emeka J ; Murty, George E</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c328t-182c6fba86ff82a8d3ee077d61e23464eb1e6f4636263af9bbb53db4ce8ea6cb3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2006</creationdate><topic>Administration, Intranasal</topic><topic>Adolescent</topic><topic>Adult</topic><topic>Airway Resistance - drug effects</topic><topic>Contraceptives, Oral, Combined - administration & dosage</topic><topic>Contraceptives, Oral, Combined - adverse effects</topic><topic>Female</topic><topic>Humans</topic><topic>Inspiratory Capacity - drug effects</topic><topic>Mucociliary Clearance - drug effects</topic><topic>Nasal Mucosa - physiopathology</topic><topic>Nasal Obstruction - chemically induced</topic><topic>Nose - drug effects</topic><topic>Nose - physiopathology</topic><topic>Pulmonary Ventilation - drug effects</topic><topic>Quality of Life</topic><topic>Rhinitis - chemically induced</topic><topic>Rhinomanometry</topic><topic>Rhinometry, Acoustic</topic><topic>Surveys and Questionnaires</topic><topic>Time Factors</topic><topic>Turbinates - physiopathology</topic><toplevel>online_resources</toplevel><creatorcontrib>Wolstenholme, Charlotte R</creatorcontrib><creatorcontrib>Philpott, Carl M</creatorcontrib><creatorcontrib>Oloto, Emeka J</creatorcontrib><creatorcontrib>Murty, George E</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><jtitle>American journal of rhinology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Wolstenholme, Charlotte R</au><au>Philpott, Carl M</au><au>Oloto, Emeka J</au><au>Murty, George E</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Does the use of the combined oral contraceptive pill cause changes in the nasal physiology in young women?</atitle><jtitle>American journal of rhinology</jtitle><addtitle>Am J Rhinol</addtitle><date>2006-03-01</date><risdate>2006</risdate><volume>20</volume><issue>2</issue><spage>238</spage><epage>240</epage><pages>238-240</pages><issn>1050-6586</issn><issn>1945-8924</issn><eissn>1539-6290</eissn><eissn>1945-8932</eissn><abstract>Changes in nasal physiology have been observed during pregnancy and the menstrual cycle. The role of female hormones in these changes is unclear. The aim is to investigate the effect of the modern combined oral contraceptive pill (COCP).
Eleven women were recruited from a family planning clinic. Anterior rhinoscopy, peak inspiratory flow rate, acoustic rhinometry, anterior rhinomanometry, mucociliary clearance time, and rhinitis quality-of-life questionnaire (RQLQ) scores were recorded at days 1 and 14 pre- and post-COCP.
Increased nasal obstruction midcycle pre-COCP, with significant differences for anterior rhinoscopy (p = 0.001) and peak inspiratory flow rate (p = 0.022), was found. No statistical difference was shown between pre- and post-COCP results apart from day 1 anterior rhinoscopy findings (p = 0.05).
The modern COCP has no significant effect on nasal physiology.</abstract><cop>United States</cop><pub>SAGE PUBLICATIONS, INC</pub><pmid>16686398</pmid><doi>10.1177/194589240602000225</doi><tpages>3</tpages></addata></record> |
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| source | MEDLINE; SAGE Complete |
| subjects | Administration, Intranasal Adolescent Adult Airway Resistance - drug effects Contraceptives, Oral, Combined - administration & dosage Contraceptives, Oral, Combined - adverse effects Female Humans Inspiratory Capacity - drug effects Mucociliary Clearance - drug effects Nasal Mucosa - physiopathology Nasal Obstruction - chemically induced Nose - drug effects Nose - physiopathology Pulmonary Ventilation - drug effects Quality of Life Rhinitis - chemically induced Rhinomanometry Rhinometry, Acoustic Surveys and Questionnaires Time Factors Turbinates - physiopathology |
| title | Does the use of the combined oral contraceptive pill cause changes in the nasal physiology in young women? |
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