Interaction of cyanine dyes with nucleic acids. 2. Spectroscopic properties of methyleneoxy analogues of Thiazole Orange
A series of asymmetric cyanine dyes based on methylenoxy benzothiazole terminal hetero-cycle was synthesized. Absorption and fluorescent properties of these dyes and their complexes with nucleic acids were investigated. The best results were obtained with 2-[(3-methyl-2(3H)-benzothiazolyliden)-methy...
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| Veröffentlicht in: | Biopolimery i kletka 1996, Vol.12 (6), p.74-81 |
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| container_end_page | 81 |
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| container_issue | 6 |
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| container_title | Biopolimery i kletka |
| container_volume | 12 |
| creator | Yarmoluk, S. M. Kovalska, V. B. Smirnova, T. V. Shandura, M. P. Kovtun, Y. P. Matsuka, G. Kh |
| description | A series of asymmetric cyanine dyes based on methylenoxy benzothiazole terminal hetero-cycle was synthesized. Absorption and fluorescent properties of these dyes and their complexes with nucleic acids were investigated. The best results were obtained with 2-[(3-methyl-2(3H)-benzothiazolyliden)-methyl]-5,6-dioxymethylene-3-methylbenzothiaz olium p-toluenesulfonate (Cyan 13). A possible model of binding monomethyne benz-thiazole cyanine dyes with double-stranded nucleic acids is proposed. |
| doi_str_mv | 10.7124/bc.000458 |
| format | Article |
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| fulltext | fulltext |
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| ispartof | Biopolimery i kletka, 1996, Vol.12 (6), p.74-81 |
| issn | 0233-7657 1993-6842 |
| language | eng |
| recordid | cdi_proquest_journals_2307132984 |
| source | Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals |
| subjects | Antifungal agents Benzothiazole Dyes Nucleic acids |
| title | Interaction of cyanine dyes with nucleic acids. 2. Spectroscopic properties of methyleneoxy analogues of Thiazole Orange |
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