Expression of the regulatory protein LndI for landomycin E production in Streptomyces globisporus 1912 is controlled by the availability of tRNA for the rare UUA codon

Abstract The gene lndI encodes the activator of landomycin biosynthesis. The utilization of LndI-EGFP fusions led us to investigate the temporal pattern of this gene expression and demonstrated the delay between lndI transcription and translation. The TTA codon in lndI is thought to be the reason fo...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	FEMS microbiology letters 2006-03, Vol.256 (1), p.30-37
Hauptverfasser:	Rebets, Yuriy V., Ostash, Bohdan O., Fukuhara, Masahiro, Nakamura, Tatsunosuke, Fedorenko, Victor O.
Format:	Artikel
Sprache:	eng
Schlagworte:	Aminoglycosides - biosynthesis Aminoglycosides - chemistry Aminoglycosides - genetics Aminoglycosides - physiology antibiotics Biosynthesis Blotting, Western - methods Codon - analysis Fluorescent Dyes - chemistry Gene expression Gene Expression Regulation, Bacterial - genetics Gene Order Green Fluorescent Proteins - chemistry Green Fluorescent Proteins - genetics Microbiology Mutagenesis, Site-Directed - methods Mutation - physiology polyketides regulation RNA, Transfer - physiology Streptomyces Streptomyces - genetics Streptomyces - physiology Time Factors Transcription Transcription, Genetic - genetics Translation tRNA
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!