Statin Safety: An Appraisal from the Adverse Event Reporting System

The adverse event (AE) profiles of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitor (statin) agents are of great interest, in particular the most recently approved statin, rosuvastatin. The forwarding of reports of AEs has been shown to be influenced by several reporting biases, i...

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Veröffentlicht in:	The American journal of cardiology 2006-04, Vol.97 (8), p.S32-S43
Hauptverfasser:	Davidson, Michael H., Clark, John A., Glass, Lucas M., Kanumalla, Anju
Format:	Artikel
Sprache:	eng
Schlagworte:	Adverse Drug Reaction Reporting Systems - statistics & numerical data Comparative analysis Databases, Factual Humans Hydroxymethylglutaryl-CoA Reductase Inhibitors - administration & dosage Hydroxymethylglutaryl-CoA Reductase Inhibitors - adverse effects Liver Failure - chemically induced Muscular Diseases - chemically induced Peripheral Nervous System Diseases - chemically induced Product Surveillance, Postmarketing Renal Insufficiency - chemically induced Safety Side effects Statins United States United States Food and Drug Administration
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