Possible Association Between 3,4-Methylenedioxymethamphetamine Abuse and Valvular Heart Disease

Valvular heart disease, inducing valvular regurgitation, has been described in users of drugs such as anorectic agents and ergot derivates. 3,4-Methylenedioxymethamphetamine (MDMA; “ecstasy”) also leads in vitro to the proliferation of cardiac valvular interstitial cells by activation of the 5-hydro...

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Veröffentlicht in:	The American journal of cardiology 2007-11, Vol.100 (9), p.1442-1445
Hauptverfasser:	Droogmans, Steven, MD, Cosyns, Bernard, MD, D’haenen, Hugo, MD, PhD, Creeten, Edwin, MD, Weytjens, Caroline, MD, Franken, Philippe R., MD, PhD, Scott, Benjamin, MD, Schoors, Danny, MD, PhD, Kemdem, Arsène, MD, Close, Laurent, MD, Vandenbossche, Jean-Luc, MD, PhD, Bechet, Serge, MD, PhD, Van Camp, Guy, MD, PhD
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Biological and medical sciences Cardiology Cardiology. Vascular system Cardiovascular Cardiovascular disease Dose-Response Relationship, Drug Drug abuse Ecstasy Endocardial and cardiac valvular diseases Female Hallucinogens - adverse effects Heart Heart Valve Diseases - chemically induced Humans Logistic Models Male Medical sciences N-Methyl-3,4-methylenedioxyamphetamine - adverse effects Substance-Related Disorders - complications Young adults
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