Meta-analysis of randomized clinical trials on the usefulness of acetylcysteine for prevention of contrast nephropathy

Multiple small studies of oral n-acetylcysteine for prevention of contrast nephropathy have been performed, demonstrating variable efficacy. We performed a meta-analysis of the randomized clinical trials to clarify the degree of benefit.

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Bibliographische Detailangaben
Veröffentlicht in:	The American journal of cardiology 2003-12, Vol.92 (12), p.1454-1458
Hauptverfasser:	Isenbarger, Daniel W., Kent, Steven M., O'Malley, Patrick G.
Format:	Artikel
Sprache:	eng
Schlagworte:	Acetylcysteine - therapeutic use Acute Kidney Injury - chemically induced Acute Kidney Injury - prevention & control Analysis Antioxidants - therapeutic use Biological and medical sciences Cardiovascular disease Clinical trials Contrast Media - adverse effects Creatinine - blood General and cellular metabolism. Vitamins Humans Medical sciences Pharmacology. Drug treatments Prevention Randomized Controlled Trials as Topic
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Beschreibung
Zusammenfassung:	Multiple small studies of oral n-acetylcysteine for prevention of contrast nephropathy have been performed, demonstrating variable efficacy. We performed a meta-analysis of the randomized clinical trials to clarify the degree of benefit.
ISSN:	0002-9149 1879-1913
DOI:	10.1016/j.amjcard.2003.08.059