Effect of abciximab on the pattern of reperfusion in patients with acute myocardial infarction treated with primary angioplasty

We investigated the effect of platelet fibrinogen receptor blockade on infarct size after primary angioplasty. Abciximab significantly reduced the time-to-peak creatine kinase without affecting enzymatic infarct size, suggesting a beneficial effect on the pattern and speed of reperfusion.

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Veröffentlicht in:The American journal of cardiology 1999-09, Vol.84 (6), p.728-730
Hauptverfasser: Brener, Sorin J, Barr, Lawrence A, Burchenal, J.E.B, Wolski, Katherine E, Effron, Mark B, Topol, Eric J
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container_end_page 730
container_issue 6
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container_title The American journal of cardiology
container_volume 84
creator Brener, Sorin J
Barr, Lawrence A
Burchenal, J.E.B
Wolski, Katherine E
Effron, Mark B
Topol, Eric J
description We investigated the effect of platelet fibrinogen receptor blockade on infarct size after primary angioplasty. Abciximab significantly reduced the time-to-peak creatine kinase without affecting enzymatic infarct size, suggesting a beneficial effect on the pattern and speed of reperfusion.
doi_str_mv 10.1016/S0002-9149(99)00421-X
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source Elsevier ScienceDirect Journals Complete
subjects Angioplasty
Biological and medical sciences
Blood. Blood coagulation. Reticuloendothelial system
Cardiology
Clinical trials
Drug therapy
Heart attacks
Medical sciences
Pharmacology. Drug treatments
title Effect of abciximab on the pattern of reperfusion in patients with acute myocardial infarction treated with primary angioplasty
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