Effect of abciximab on the pattern of reperfusion in patients with acute myocardial infarction treated with primary angioplasty

Effect of abciximab on the pattern of reperfusion in patients with acute myocardial infarction treated with primary angioplasty

We investigated the effect of platelet fibrinogen receptor blockade on infarct size after primary angioplasty. Abciximab significantly reduced the time-to-peak creatine kinase without affecting enzymatic infarct size, suggesting a beneficial effect on the pattern and speed of reperfusion.

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Veröffentlicht in:The American journal of cardiology 1999-09, Vol.84 (6), p.728-730
Hauptverfasser: Brener, Sorin J, Barr, Lawrence A, Burchenal, J.E.B, Wolski, Katherine E, Effron, Mark B, Topol, Eric J
Format: Artikel
Sprache:eng
Schlagworte:
Angioplasty
Biological and medical sciences
Blood. Blood coagulation. Reticuloendothelial system
Cardiology
Clinical trials
Drug therapy
Heart attacks
Medical sciences
Pharmacology. Drug treatments
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Zusammenfassung:We investigated the effect of platelet fibrinogen receptor blockade on infarct size after primary angioplasty. Abciximab significantly reduced the time-to-peak creatine kinase without affecting enzymatic infarct size, suggesting a beneficial effect on the pattern and speed of reperfusion.
ISSN:0002-9149
1879-1913
DOI:10.1016/S0002-9149(99)00421-X