Usefulness of the myocardial performance index for early detection of anthracycline-induced cardiotoxicity in children
Standard echocardiographic measurements of systolic function in patients receiving anthracycline may miss early signs of ventricular dysfunction. In this study, we utilized a global index of sytolic and diastolic ventricular function, the myocardial performance index, and found evidence of significa...
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| Veröffentlicht in: | The American journal of cardiology 2001-05, Vol.87 (9), p.1120-1122 |
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| container_title | The American journal of cardiology |
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| creator | Eidem, Benjamin W Sapp, Brian G Suarez, Carlos R Cetta, Frank |
| description | Standard echocardiographic measurements of systolic function in patients receiving anthracycline may miss early signs of ventricular dysfunction. In this study, we utilized a global index of sytolic and diastolic ventricular function, the myocardial performance index, and found evidence of significant cardiotoxicity at a lower cumulative dosage of anthracycline than previously recognized. |
| doi_str_mv | 10.1016/S0002-9149(01)01476-X |
| format | Article |
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| source | MEDLINE; Access via ScienceDirect (Elsevier) |
| subjects | Adolescent Antibiotics, Antineoplastic - adverse effects Biological and medical sciences Cardiology Cardiovascular disease Child Child, Preschool Children & youth Drug toxicity and drugs side effects treatment Echocardiography, Doppler Female Heart Diseases - chemically induced Heart Diseases - diagnostic imaging Humans Infant Male Medical research Medical sciences Observer Variation Pharmacology. Drug treatments Predictive Value of Tests Retrospective Studies Toxicity: cardiovascular system Ultrasonic imaging Ventricular Dysfunction, Left - chemically induced Ventricular Dysfunction, Left - diagnostic imaging |
| title | Usefulness of the myocardial performance index for early detection of anthracycline-induced cardiotoxicity in children |
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