Weight-adjusted dosing of TNK-tissue plasminogen activator and its relation to angiographic outcomes in the thrombolysis in myocardial infarction 10B trial

Fixed doses of thrombolytic agents are generally administered to patients of varying body weights, and the dose-response relation may be confounded by the variability in patient weight. We hypothesized that higher doses of TNK-tissue plasminogen activator (tPA) per unit body weight would be related...

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Veröffentlicht in:	The American journal of cardiology 1999-11, Vol.84 (9), p.976-980
Hauptverfasser:	Gibson, C.Michael, Cannon, Christopher P, Murphy, Sabina A, Adgey, A.A.Jennifer, Schweiger, Marc J, Sequeira, Rafael F, Grollier, Gilles, Fox, Norma Lynn, Berioli, Silvano, Weaver, W.Douglas, Van de Werf, Frans, Braunwald, Eugene
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Blood. Blood coagulation. Reticuloendothelial system Cardiology Cardiovascular disease Heart attacks Medical sciences Pharmacology. Drug treatments Weight
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