Mechanisms of P2X7 receptor-mediated ERK1/2 phosphorylation in human astrocytoma cells

Astrocytes are involved in normal and pathological brain functions, where they become activated and undergo reactive gliosis. Astrocytes have been shown to respond to extracellular nucleotides via the activation of P2 receptors, either G protein-coupled P2Y receptors or P2X receptors that are ligand...

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Veröffentlicht in:American Journal of Physiology: Cell Physiology 2003-02, Vol.53 (2), p.C571-C581
Hauptverfasser: GENDRON, Fernand-Pierre, NEARY, Joseph T, THEISS, Patty M, SUN, Grace Y, GONZALEZ, Fernando A, WEISMAN, Gary A
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Sprache:eng
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