Interferon-γ induces a decrease in the intracellular calcium pump in a human salivary gland cell line

Interferon-gamma (IFN-gamma) tumor necrosis factor-alpha. (TNF-alpha) induces antiproliferation and intracellular Ca2+ store depletion in a human submandibular ductal cell line (HSG), which can be reversed on cytokine removal.Here we have examined a possible mechanism for the IFN-gamma-induced intra...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	American Journal of Physiology: Cell Physiology 1997-12, Vol.42 (6), p.C2030-C2036
Hauptverfasser:	MEEHAN, S, WU, A. J, KANG, E. C, SAKAI, T, AMBUDKAR, I. S
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Body fluids Calcium Cell physiology Cellular biology Fundamental and applied biological sciences. Psychology Molecular and cellular biology Proteins Responses to growth factors, tumor promotors, other factors
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	Interferon-gamma (IFN-gamma) tumor necrosis factor-alpha. (TNF-alpha) induces antiproliferation and intracellular Ca2+ store depletion in a human submandibular ductal cell line (HSG), which can be reversed on cytokine removal.Here we have examined a possible mechanism for the IFN-gamma-induced intracellular Ca2+ store depletion.
ISSN:	0363-6143 1522-1563