System-specific O2 sensitivity of the tandem pore domain K+ channel TASK-1

Hypoxic inhibition of TASK-1, a tandem pore domain background K+ channel, provides a critical link between reduced O2 levels and physiological responses in various cell types. Here, we examined the expression and O2 sensitivity of TASK-1 in immortalized adrenomedullary chromaffin (MAH) cells. In phy...

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Veröffentlicht in:	American Journal of Physiology: Cell Physiology 2004-02, Vol.55 (2), p.C391-C397
Hauptverfasser:	JOHNSON, Rosalyn P, O'KELLY, Ita M, FEARON, Ian M
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Cell membranes. Ionic channels. Membrane pores Cell structures and functions Cells Fundamental and applied biological sciences. Psychology Molecular and cellular biology Oxygen Potassium
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