Cytosolic phospholipase A^sub 2^-[alpha] is an early apoptotic activator in PEDF-induced endothelial cell apoptosis

Pigment epithelium-derived factor (PEDF) is an intrinsic antiangiogenic factor and a potential therapeutic agent. Previously, we discovered the mechanism of PEDF-induced apoptosis of human umbilical vein endothelial cells (HUVECs) as sequential induction/activation of p38 mitogen-activated protein k...

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Veröffentlicht in:American Journal of Physiology: Cell Physiology 2009-02, Vol.296 (2), p.C273
Hauptverfasser: Ho, Tsung-Chuan, Chen, Show-Li, Yang, Yuh-Cheng, Lo, Tzu-Hsiu, Hsieh, Jui-Wen, Cheng, Huey-Chuan, Tsao, Yeou-Ping
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Sprache:eng
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