Biosynthetic and growth abnormalities are associated with high-level expression of CFTR in heterologous cells

An inducible gene amplification system was utilized to examine the effects of overexpression of cystic fibrosis transmembrane conductance regulator (CFTR) in vitro. CFTR overexpression is capable of inducing its own downregulation.

Bibliographische Detailangaben

Veröffentlicht in:	American Journal of Physiology: Cell Physiology 1996, Vol.39 (1), p.C341-C351
Hauptverfasser:	SCHIAVI, S. C, ABDELKADER, N, REBER, S, PENNINGTON, S, NARAYANA, R, MCPHERSON, J. M, SMITH, A. E, HOPPE, H. IV, CHENG, S. H
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Cell cycle, cell proliferation Cell physiology Cellular biology Cystic fibrosis Fundamental and applied biological sciences. Psychology Genes Membranes Molecular and cellular biology
Online-Zugang:	Volltext
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