Biosynthetic and growth abnormalities are associated with high-level expression of CFTR in heterologous cells
An inducible gene amplification system was utilized to examine the effects of overexpression of cystic fibrosis transmembrane conductance regulator (CFTR) in vitro. CFTR overexpression is capable of inducing its own downregulation.
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| Veröffentlicht in: | American Journal of Physiology: Cell Physiology 1996, Vol.39 (1), p.C341-C351 |
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| container_end_page | C351 |
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| container_issue | 1 |
| container_start_page | C341 |
| container_title | American Journal of Physiology: Cell Physiology |
| container_volume | 39 |
| creator | SCHIAVI, S. C ABDELKADER, N REBER, S PENNINGTON, S NARAYANA, R MCPHERSON, J. M SMITH, A. E HOPPE, H. IV CHENG, S. H |
| description | An inducible gene amplification system was utilized to examine the effects of overexpression of cystic fibrosis transmembrane conductance regulator (CFTR) in vitro. CFTR overexpression is capable of inducing its own downregulation. |
| format | Article |
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| fulltext | fulltext |
| identifier | ISSN: 0363-6143 |
| ispartof | American Journal of Physiology: Cell Physiology, 1996, Vol.39 (1), p.C341-C351 |
| issn | 0363-6143 1522-1563 |
| language | eng |
| recordid | cdi_proquest_journals_230321338 |
| source | Alma/SFX Local Collection |
| subjects | Biological and medical sciences Cell cycle, cell proliferation Cell physiology Cellular biology Cystic fibrosis Fundamental and applied biological sciences. Psychology Genes Membranes Molecular and cellular biology |
| title | Biosynthetic and growth abnormalities are associated with high-level expression of CFTR in heterologous cells |
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