Comparative Toxicity of CuZn Nanoparticles with Different Physical and Chemical Characteristics

In the experiment, the biological activity of copper and zinc alloy nanoparticles prepared by gas phase synthesis in an argon atmosphere was assessed. Nanoparticle preparations differed in phase composition and specific surface for CuZnNPs1 - 36 m2/g, CuZnNPs2 - 22 and CuZnNPs3 NP - 15 m2/g. As the...

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Veröffentlicht in:Oriental journal of chemistry 2019-01, Vol.35 (3), p.973-981
Hauptverfasser: Miroshnikov, Sergey, Sizova, Elena, Yausheva, Elena, Uimin, Michael, Konev, Alexander, Minin, Artem, Yermakov, Anatoly, Nikiyan, Hike
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container_end_page 981
container_issue 3
container_start_page 973
container_title Oriental journal of chemistry
container_volume 35
creator Miroshnikov, Sergey
Sizova, Elena
Yausheva, Elena
Uimin, Michael
Konev, Alexander
Minin, Artem
Yermakov, Anatoly
Nikiyan, Hike
description In the experiment, the biological activity of copper and zinc alloy nanoparticles prepared by gas phase synthesis in an argon atmosphere was assessed. Nanoparticle preparations differed in phase composition and specific surface for CuZnNPs1 - 36 m2/g, CuZnNPs2 - 22 and CuZnNPs3 NP - 15 m2/g. As the test cultures, E.coli K12 TG1 pF1, E.coli K12 MG1655 katG::lux, E.coli MG1655 pRecA-lux, E.coli K12 MG1655 psoxS::lux were used. As the results showed, phase composition and specific surface area of nanoparticles were their toxicity factors. CuZnNPs3 is the most toxic among the studied samples, the percentage of zinc phase in it, in comparison with other tested powders, is the largest (52.3%), and the percentage of metallic copper is the smallest (7.9%). Within further works is to carry out controlled synthesis that will allow changing the toxicity of the nanoparticles under study by phase composition and specific surface.
doi_str_mv 10.13005/ojc/350308
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Nanoparticle preparations differed in phase composition and specific surface for CuZnNPs1 - 36 m2/g, CuZnNPs2 - 22 and CuZnNPs3 NP - 15 m2/g. As the test cultures, E.coli K12 TG1 pF1, E.coli K12 MG1655 katG::lux, E.coli MG1655 pRecA-lux, E.coli K12 MG1655 psoxS::lux were used. As the results showed, phase composition and specific surface area of nanoparticles were their toxicity factors. CuZnNPs3 is the most toxic among the studied samples, the percentage of zinc phase in it, in comparison with other tested powders, is the largest (52.3%), and the percentage of metallic copper is the smallest (7.9%). 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subjects Alloys
Argon
Bacteria
Biological activity
Biomedical materials
Copper
E coli
Experiments
Luminescence quenching
Nanoalloys
Nanomaterials
Nanoparticles
Organic chemistry
Phase composition
Specific surface
Synthesis
Toxicity
Toxicology
Vapor phases
Zinc base alloys
title Comparative Toxicity of CuZn Nanoparticles with Different Physical and Chemical Characteristics
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