Wheat Bran Decreases Aberrant Crypt Foci, Preserves Normal Proliferation, and Increases Intraluminal Butyrate Levels in Experimental Colon Cancer

Background: Dietary wheat bran protects against colon cancer, but the mechanism(s) of this effect is not known. Butyrate, produced by colonic bacterial fermentation of dietary polysaccharides, such as wheat bran, induces apoptosis and decreases proliferation in colon cancer cell lines. Whether simil...

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Veröffentlicht in:	JPEN. Journal of parenteral and enteral nutrition 1999-09, Vol.23 (5), p.269-278
Hauptverfasser:	Compher, Charlene W., Frankel, Wendy L., Tazelaar, John, Lawson, John A., McKinney, Shortie, Segall, Stanley, Kinosian, Bruce P., Williams, Noel N., Rombeau, John L.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Anticarcinogenic Agents - pharmacology Anticarcinogenic Agents - therapeutic use Apoptosis Butyrates - metabolism Cell Division Colon - pathology Colonic Neoplasms - metabolism Colonic Neoplasms - pathology Colonic Neoplasms - prevention & control Dietary Fiber - pharmacology Dietary Fiber - therapeutic use Feces - chemistry Male Rats Rats, Inbred F344 Triticum
Online-Zugang:	Volltext
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