Parenteral Nutrition and Fasting Reduces Mucosal Addressin Cellular Adhesion Molecule-1 (MAdCAM-1) mRNA in Peyer's Patches of Mice
Background: Mucosal addressin cellular adhesion molecule-1 (MAdCAM-1) in Peyer's patches (PP) is the gateway molecule for cellular migration into the mucosal immune system. Lack of enteral feeding during parenteral nutrition (PN) rapidly decreases PP MAdCAM-1, leading to drops in mucosal T and...
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| creator | Gomez, F. Enrique Lan, Jinggang Kang, Woodae Ueno, Chikara Kudsk, Kenneth A. |
| description | Background: Mucosal addressin cellular adhesion molecule-1
(MAdCAM-1) in Peyer's patches (PP) is the gateway molecule for cellular
migration into the mucosal immune system. Lack of enteral feeding during
parenteral nutrition (PN) rapidly decreases PP MAdCAM-1, leading to drops in
mucosal T and B cells and intestinal and respiratory IgA. We determined the
molecular events associated with MAdCAM-1 mRNA and protein during PN (short
and long term) and fasting (1 and 2 days). Methods: Experiment 1:
Cannulated mice received PN for 8 hours (short-term PN, n = 6) or chow +
saline (chow, n = 6). Experiment 2: Cannulated mice received PN (long-term PN,
n = 4) or chow (n = 3) for 5 days. Experiment 3: Noncannulated chow mice were
fasted for 1 and 2 days (n = 2/time). Total cellular RNA from the PP was
quantified for MAdCAM-1 mRNA by real-time polymerase chain reaction (PCR).
MAdCAM-1 protein was measured by Western blot. Results: PN rapidly
down-regulated MAdCAM-1 gene expression. After 8 hours of PN with lack of
enteral feeding, MAdCAM-1 mRNA levels dropped 20% (0.8-fold vs chow,
p > .05); 5 days of PN reduced MAd-CAM-1 levels 64% (0.34-fold
vs chow, p < .05). PN reduced MAdCAM-1 protein levels by
30% (chow: 329 ± 14 vs PN: 230 ± 35, p <
.05) after 5 days. Fasting of uncannulated mice decreased MAdCAM-1 mRNA levels
by 16% (0.84-fold, p < .05) at day 1 and 30% (0.7-fold, p< .05) by day 2 compared with chow. Conclusions: Both PN with lack
of enteral feeding and fasting down-regulate MAdCAM-1 mRNA and protein levels
in PP. The MAdCAM-1 changes are due to lack of enteral stimulation rather than
toxic effects of PN.
Short-term (8 hours) parenteral feeding, long-term (5 days) parenteral feeding, and fasting down-regulate murine Peyer’s patch (PP) mucosal addressin cellular adhesion molecule-1 (dCAM-1) gene expression (mA) and protein levels. |
| doi_str_mv | 10.1177/014860710703100147 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_journals_230207434</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sage_id>10.1177_014860710703100147</sage_id><sourcerecordid>1191889361</sourcerecordid><originalsourceid>FETCH-LOGICAL-c4477-69bbb1ebc24c44db1f811d8da0f5a6c33f2374cb65dd4e77847611252a2e7ab63</originalsourceid><addsrcrecordid>eNqN0E1r3DAQBmARGpJN2j_QQxGFkObgZkbWWt6jWZJ-EG-X0J6NLI1TB62dSDZhr_3llbsLeyiUnoTE886MhrG3CB8RlboGlHkGCkFBihBv6ojNcCExEVLKV2w2gWQSp-wshEcASDOAE3aKSkA0MGO_1tpTN5DXjq_GwbdD23dcd5bf6jC03QO_JzsaCrwcTR-iKqz1FELb8SU5Nzrt49NPClOu7B2Z0VGC_ENZ2GVRJnjFN_ergke_pi35y8DXejAxwPuGl62h1-y40S7Qm_15zn7c3nxffk7uvn36sizuEiOlUkm2qOsaqTZCxgdbY5Mj2txqaOY6M2naiFRJU2dzayUplUuVIYq50IKUrrP0nL3f1X3y_fNIYage-9F3sWUlUhCgZCojEjtkfB-Cp6Z68u1G-22FUE1br_7eegy921ce6w3ZQ2S_5ggu9kAHo13jdWfacHC5xMUin1y-cy-to-1_tK6-rm9WAH9muN5Fg36gw8_-MfVv96iksw</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>230207434</pqid></control><display><type>article</type><title>Parenteral Nutrition and Fasting Reduces Mucosal Addressin Cellular Adhesion Molecule-1 (MAdCAM-1) mRNA in Peyer's Patches of Mice</title><source>MEDLINE</source><source>Wiley Online Library Journals Frontfile Complete</source><source>Alma/SFX Local Collection</source><creator>Gomez, F. Enrique ; Lan, Jinggang ; Kang, Woodae ; Ueno, Chikara ; Kudsk, Kenneth A.</creator><creatorcontrib>Gomez, F. Enrique ; Lan, Jinggang ; Kang, Woodae ; Ueno, Chikara ; Kudsk, Kenneth A.</creatorcontrib><description>Background: Mucosal addressin cellular adhesion molecule-1
(MAdCAM-1) in Peyer's patches (PP) is the gateway molecule for cellular
migration into the mucosal immune system. Lack of enteral feeding during
parenteral nutrition (PN) rapidly decreases PP MAdCAM-1, leading to drops in
mucosal T and B cells and intestinal and respiratory IgA. We determined the
molecular events associated with MAdCAM-1 mRNA and protein during PN (short
and long term) and fasting (1 and 2 days). Methods: Experiment 1:
Cannulated mice received PN for 8 hours (short-term PN, n = 6) or chow +
saline (chow, n = 6). Experiment 2: Cannulated mice received PN (long-term PN,
n = 4) or chow (n = 3) for 5 days. Experiment 3: Noncannulated chow mice were
fasted for 1 and 2 days (n = 2/time). Total cellular RNA from the PP was
quantified for MAdCAM-1 mRNA by real-time polymerase chain reaction (PCR).
MAdCAM-1 protein was measured by Western blot. Results: PN rapidly
down-regulated MAdCAM-1 gene expression. After 8 hours of PN with lack of
enteral feeding, MAdCAM-1 mRNA levels dropped 20% (0.8-fold vs chow,
p > .05); 5 days of PN reduced MAd-CAM-1 levels 64% (0.34-fold
vs chow, p < .05). PN reduced MAdCAM-1 protein levels by
30% (chow: 329 ± 14 vs PN: 230 ± 35, p <
.05) after 5 days. Fasting of uncannulated mice decreased MAdCAM-1 mRNA levels
by 16% (0.84-fold, p < .05) at day 1 and 30% (0.7-fold, p< .05) by day 2 compared with chow. Conclusions: Both PN with lack
of enteral feeding and fasting down-regulate MAdCAM-1 mRNA and protein levels
in PP. The MAdCAM-1 changes are due to lack of enteral stimulation rather than
toxic effects of PN.
Short-term (8 hours) parenteral feeding, long-term (5 days) parenteral feeding, and fasting down-regulate murine Peyer’s patch (PP) mucosal addressin cellular adhesion molecule-1 (dCAM-1) gene expression (mA) and protein levels.</description><identifier>ISSN: 0148-6071</identifier><identifier>EISSN: 1941-2444</identifier><identifier>DOI: 10.1177/014860710703100147</identifier><identifier>PMID: 17202440</identifier><identifier>CODEN: JPENDU</identifier><language>eng</language><publisher>Silver Spring, MD: SAGE Publications</publisher><subject>Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy ; Animals ; Biological and medical sciences ; Blotting, Western ; Cell Adhesion Molecules - metabolism ; Emergency and intensive care: metabolism and nutrition disorders. Enteral and parenteral nutrition ; Emergency and intensive postoperative care (general aspects). Pathophysiology of surgery ; Fasting - metabolism ; Gene Expression Regulation ; General aspects ; Immunity, Mucosal - physiology ; Intensive care medicine ; Male ; Medical sciences ; Mice ; Mice, Inbred ICR ; Parenteral Nutrition ; Peyer's Patches - immunology ; Peyer's Patches - metabolism ; Polymerase Chain Reaction ; Random Allocation</subject><ispartof>JPEN. Journal of parenteral and enteral nutrition, 2007-01, Vol.31 (1), p.47-52</ispartof><rights>American Society for Parenteral and Enteral Nutrition</rights><rights>2007 by The American Society for Parenteral and Enteral Nutrition</rights><rights>2007 INIST-CNRS</rights><rights>Copyright American Society for Parenteral and Enteral Nutrition Jan/Feb 2007</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c4477-69bbb1ebc24c44db1f811d8da0f5a6c33f2374cb65dd4e77847611252a2e7ab63</citedby><cites>FETCH-LOGICAL-c4477-69bbb1ebc24c44db1f811d8da0f5a6c33f2374cb65dd4e77847611252a2e7ab63</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1177%2F014860710703100147$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1177%2F014860710703100147$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,776,780,1411,4009,27902,27903,27904,45553,45554</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=18419980$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/17202440$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Gomez, F. Enrique</creatorcontrib><creatorcontrib>Lan, Jinggang</creatorcontrib><creatorcontrib>Kang, Woodae</creatorcontrib><creatorcontrib>Ueno, Chikara</creatorcontrib><creatorcontrib>Kudsk, Kenneth A.</creatorcontrib><title>Parenteral Nutrition and Fasting Reduces Mucosal Addressin Cellular Adhesion Molecule-1 (MAdCAM-1) mRNA in Peyer's Patches of Mice</title><title>JPEN. Journal of parenteral and enteral nutrition</title><addtitle>JPEN J Parenter Enteral Nutr</addtitle><description>Background: Mucosal addressin cellular adhesion molecule-1
(MAdCAM-1) in Peyer's patches (PP) is the gateway molecule for cellular
migration into the mucosal immune system. Lack of enteral feeding during
parenteral nutrition (PN) rapidly decreases PP MAdCAM-1, leading to drops in
mucosal T and B cells and intestinal and respiratory IgA. We determined the
molecular events associated with MAdCAM-1 mRNA and protein during PN (short
and long term) and fasting (1 and 2 days). Methods: Experiment 1:
Cannulated mice received PN for 8 hours (short-term PN, n = 6) or chow +
saline (chow, n = 6). Experiment 2: Cannulated mice received PN (long-term PN,
n = 4) or chow (n = 3) for 5 days. Experiment 3: Noncannulated chow mice were
fasted for 1 and 2 days (n = 2/time). Total cellular RNA from the PP was
quantified for MAdCAM-1 mRNA by real-time polymerase chain reaction (PCR).
MAdCAM-1 protein was measured by Western blot. Results: PN rapidly
down-regulated MAdCAM-1 gene expression. After 8 hours of PN with lack of
enteral feeding, MAdCAM-1 mRNA levels dropped 20% (0.8-fold vs chow,
p > .05); 5 days of PN reduced MAd-CAM-1 levels 64% (0.34-fold
vs chow, p < .05). PN reduced MAdCAM-1 protein levels by
30% (chow: 329 ± 14 vs PN: 230 ± 35, p <
.05) after 5 days. Fasting of uncannulated mice decreased MAdCAM-1 mRNA levels
by 16% (0.84-fold, p < .05) at day 1 and 30% (0.7-fold, p< .05) by day 2 compared with chow. Conclusions: Both PN with lack
of enteral feeding and fasting down-regulate MAdCAM-1 mRNA and protein levels
in PP. The MAdCAM-1 changes are due to lack of enteral stimulation rather than
toxic effects of PN.
Short-term (8 hours) parenteral feeding, long-term (5 days) parenteral feeding, and fasting down-regulate murine Peyer’s patch (PP) mucosal addressin cellular adhesion molecule-1 (dCAM-1) gene expression (mA) and protein levels.</description><subject>Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy</subject><subject>Animals</subject><subject>Biological and medical sciences</subject><subject>Blotting, Western</subject><subject>Cell Adhesion Molecules - metabolism</subject><subject>Emergency and intensive care: metabolism and nutrition disorders. Enteral and parenteral nutrition</subject><subject>Emergency and intensive postoperative care (general aspects). Pathophysiology of surgery</subject><subject>Fasting - metabolism</subject><subject>Gene Expression Regulation</subject><subject>General aspects</subject><subject>Immunity, Mucosal - physiology</subject><subject>Intensive care medicine</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Mice</subject><subject>Mice, Inbred ICR</subject><subject>Parenteral Nutrition</subject><subject>Peyer's Patches - immunology</subject><subject>Peyer's Patches - metabolism</subject><subject>Polymerase Chain Reaction</subject><subject>Random Allocation</subject><issn>0148-6071</issn><issn>1941-2444</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2007</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>BEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><recordid>eNqN0E1r3DAQBmARGpJN2j_QQxGFkObgZkbWWt6jWZJ-EG-X0J6NLI1TB62dSDZhr_3llbsLeyiUnoTE886MhrG3CB8RlboGlHkGCkFBihBv6ojNcCExEVLKV2w2gWQSp-wshEcASDOAE3aKSkA0MGO_1tpTN5DXjq_GwbdD23dcd5bf6jC03QO_JzsaCrwcTR-iKqz1FELb8SU5Nzrt49NPClOu7B2Z0VGC_ENZ2GVRJnjFN_ergke_pi35y8DXejAxwPuGl62h1-y40S7Qm_15zn7c3nxffk7uvn36sizuEiOlUkm2qOsaqTZCxgdbY5Mj2txqaOY6M2naiFRJU2dzayUplUuVIYq50IKUrrP0nL3f1X3y_fNIYage-9F3sWUlUhCgZCojEjtkfB-Cp6Z68u1G-22FUE1br_7eegy921ce6w3ZQ2S_5ggu9kAHo13jdWfacHC5xMUin1y-cy-to-1_tK6-rm9WAH9muN5Fg36gw8_-MfVv96iksw</recordid><startdate>200701</startdate><enddate>200701</enddate><creator>Gomez, F. Enrique</creator><creator>Lan, Jinggang</creator><creator>Kang, Woodae</creator><creator>Ueno, Chikara</creator><creator>Kudsk, Kenneth A.</creator><general>SAGE Publications</general><general>ASPEN</general><general>American Society for Parenteral and Enteral Nutrition</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7RV</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8AO</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AN0</scope><scope>BEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>KB0</scope><scope>M0S</scope><scope>M1P</scope><scope>NAPCQ</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope></search><sort><creationdate>200701</creationdate><title>Parenteral Nutrition and Fasting Reduces Mucosal Addressin Cellular Adhesion Molecule-1 (MAdCAM-1) mRNA in Peyer's Patches of Mice</title><author>Gomez, F. Enrique ; Lan, Jinggang ; Kang, Woodae ; Ueno, Chikara ; Kudsk, Kenneth A.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4477-69bbb1ebc24c44db1f811d8da0f5a6c33f2374cb65dd4e77847611252a2e7ab63</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2007</creationdate><topic>Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy</topic><topic>Animals</topic><topic>Biological and medical sciences</topic><topic>Blotting, Western</topic><topic>Cell Adhesion Molecules - metabolism</topic><topic>Emergency and intensive care: metabolism and nutrition disorders. Enteral and parenteral nutrition</topic><topic>Emergency and intensive postoperative care (general aspects). Pathophysiology of surgery</topic><topic>Fasting - metabolism</topic><topic>Gene Expression Regulation</topic><topic>General aspects</topic><topic>Immunity, Mucosal - physiology</topic><topic>Intensive care medicine</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Mice</topic><topic>Mice, Inbred ICR</topic><topic>Parenteral Nutrition</topic><topic>Peyer's Patches - immunology</topic><topic>Peyer's Patches - metabolism</topic><topic>Polymerase Chain Reaction</topic><topic>Random Allocation</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Gomez, F. Enrique</creatorcontrib><creatorcontrib>Lan, Jinggang</creatorcontrib><creatorcontrib>Kang, Woodae</creatorcontrib><creatorcontrib>Ueno, Chikara</creatorcontrib><creatorcontrib>Kudsk, Kenneth A.</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Nursing & Allied Health Database</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>British Nursing Database</collection><collection>eLibrary</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Nursing & Allied Health Premium</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><jtitle>JPEN. Journal of parenteral and enteral nutrition</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Gomez, F. Enrique</au><au>Lan, Jinggang</au><au>Kang, Woodae</au><au>Ueno, Chikara</au><au>Kudsk, Kenneth A.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Parenteral Nutrition and Fasting Reduces Mucosal Addressin Cellular Adhesion Molecule-1 (MAdCAM-1) mRNA in Peyer's Patches of Mice</atitle><jtitle>JPEN. Journal of parenteral and enteral nutrition</jtitle><addtitle>JPEN J Parenter Enteral Nutr</addtitle><date>2007-01</date><risdate>2007</risdate><volume>31</volume><issue>1</issue><spage>47</spage><epage>52</epage><pages>47-52</pages><issn>0148-6071</issn><eissn>1941-2444</eissn><coden>JPENDU</coden><abstract>Background: Mucosal addressin cellular adhesion molecule-1
(MAdCAM-1) in Peyer's patches (PP) is the gateway molecule for cellular
migration into the mucosal immune system. Lack of enteral feeding during
parenteral nutrition (PN) rapidly decreases PP MAdCAM-1, leading to drops in
mucosal T and B cells and intestinal and respiratory IgA. We determined the
molecular events associated with MAdCAM-1 mRNA and protein during PN (short
and long term) and fasting (1 and 2 days). Methods: Experiment 1:
Cannulated mice received PN for 8 hours (short-term PN, n = 6) or chow +
saline (chow, n = 6). Experiment 2: Cannulated mice received PN (long-term PN,
n = 4) or chow (n = 3) for 5 days. Experiment 3: Noncannulated chow mice were
fasted for 1 and 2 days (n = 2/time). Total cellular RNA from the PP was
quantified for MAdCAM-1 mRNA by real-time polymerase chain reaction (PCR).
MAdCAM-1 protein was measured by Western blot. Results: PN rapidly
down-regulated MAdCAM-1 gene expression. After 8 hours of PN with lack of
enteral feeding, MAdCAM-1 mRNA levels dropped 20% (0.8-fold vs chow,
p > .05); 5 days of PN reduced MAd-CAM-1 levels 64% (0.34-fold
vs chow, p < .05). PN reduced MAdCAM-1 protein levels by
30% (chow: 329 ± 14 vs PN: 230 ± 35, p <
.05) after 5 days. Fasting of uncannulated mice decreased MAdCAM-1 mRNA levels
by 16% (0.84-fold, p < .05) at day 1 and 30% (0.7-fold, p< .05) by day 2 compared with chow. Conclusions: Both PN with lack
of enteral feeding and fasting down-regulate MAdCAM-1 mRNA and protein levels
in PP. The MAdCAM-1 changes are due to lack of enteral stimulation rather than
toxic effects of PN.
Short-term (8 hours) parenteral feeding, long-term (5 days) parenteral feeding, and fasting down-regulate murine Peyer’s patch (PP) mucosal addressin cellular adhesion molecule-1 (dCAM-1) gene expression (mA) and protein levels.</abstract><cop>Silver Spring, MD</cop><pub>SAGE Publications</pub><pmid>17202440</pmid><doi>10.1177/014860710703100147</doi><tpages>6</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0148-6071 |
| ispartof | JPEN. Journal of parenteral and enteral nutrition, 2007-01, Vol.31 (1), p.47-52 |
| issn | 0148-6071 1941-2444 |
| language | eng |
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| source | MEDLINE; Wiley Online Library Journals Frontfile Complete; Alma/SFX Local Collection |
| subjects | Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy Animals Biological and medical sciences Blotting, Western Cell Adhesion Molecules - metabolism Emergency and intensive care: metabolism and nutrition disorders. Enteral and parenteral nutrition Emergency and intensive postoperative care (general aspects). Pathophysiology of surgery Fasting - metabolism Gene Expression Regulation General aspects Immunity, Mucosal - physiology Intensive care medicine Male Medical sciences Mice Mice, Inbred ICR Parenteral Nutrition Peyer's Patches - immunology Peyer's Patches - metabolism Polymerase Chain Reaction Random Allocation |
| title | Parenteral Nutrition and Fasting Reduces Mucosal Addressin Cellular Adhesion Molecule-1 (MAdCAM-1) mRNA in Peyer's Patches of Mice |
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