Safety and efficacy of Option B+ ART in Malawi: few severe maternal toxicity events or infant HIV infections among pregnant women initiating tenofovir/lamivudine/efavirenz

Objectives Malawi's Option B+ universal antiretroviral therapy (ART) program for pregnant and breastfeeding women does not include routine laboratory monitoring. We report safety outcomes of pregnant women who initiated ART through Option B+. Methods We analysed 12‐month data from an observatio...

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Veröffentlicht in:	Tropical medicine & international health 2019-10, Vol.24 (10), p.1221-1228
Hauptverfasser:	Harrington, Bryna J., DiPrete, Bethany L., Jumbe, Allan N., Ngongondo, McNeil, Limarzi, Laura, Wallie, Shaphil D., Chagomerana, Maganizo B., Hosseinipour, Mina C.
Format:	Artikel
Sprache:	eng
Schlagworte:	Antiretroviral agents Antiretroviral drugs Antiretroviral therapy Birth weight Breast feeding CD4 antigen Creatinine Efavirenz grossesse Hemoglobin HIV HIV infection Human immunodeficiency virus Incidence Infants infection par le VIH Infections Infectious diseases Laboratories Lamivudine Malawi Monitoring Nucleic acids Option B Parturition Pregnancy Premature birth prevention of mother to child transmission prévention de la transmission mère‐enfant Ribonucleic acid RNA Safety safety and efficacy sécurité et efficacité Tenofovir Toxicity
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