Bid activation in kidney cells following ATP depletion in vitro and ischemia in vivo
Bid is a proapoptotic Bcl-2 family protein, which on activation translocates to mitochondria and induces damage to the organelles. Activation of Bid depends on its proteolytic processing into truncated forms of tBid. Bid is highly expressed in the kidneys; however, little is known about its role in...
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Veröffentlicht in: | American journal of physiology. Renal physiology 2004-04, Vol.55 (4), p.F803-F809 |
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Sprache: | eng |
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