Phosphatase inhibitors increase the open probability of ENaC in A6 cells

We studied the cellular phosphatase inhibitors okadaic acid (OKA), calyculin A, and microcystin on the epithelial sodium channel (ENaC) in A6 renal cells. OKA increased the amiloride-sensitive current after tilde30 min with maximal stimulation at 1-2 h. Fluctuation analysis of cell-attached patches...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	American journal of physiology. Renal physiology 2002-11, Vol.52 (5), p.F1030-F1045
Hauptverfasser:	BECCHETTI, A, MALIK, B, YUE, G, DUCHATELLE, P, AL-KHALILI, O, KLEYMAN, T. R, EATON, D. C
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Cells Fundamental and applied biological sciences. Psychology Kidneys Phosphates Vertebrates: urinary system
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!