Pharmacogenomic effect of vitamin E on kidney structure and function in transgenic mice with the haptoglobin 2-2 genotype and diabetes mellitus

1 Ambulatory Nephrology Unit, Rambam-Health Care Campus, 2 Faculty of Medicine, Technion Haifa, Israel; and 3 Semmelweise University, Faculty of Medicine, Budapest, Hungary Submitted 2 November 2008 ; accepted in final form 21 January 2009 Polymorphic loci regulating oxidative stress are potential s...

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Veröffentlicht in:	American journal of physiology. Renal physiology 2009-04, Vol.296 (4), p.F830-F838
Hauptverfasser:	Nakhoul, Farid M, Miller-Lotan, Rachel, Awad, Hoda, Asleh, Rabea, Jad, Kheir, Nakhoul, Nakhoul, Asaf, Roy, Abu-Saleh, Niroz, Levy, Andrew P
Format:	Artikel
Sprache:	eng
Schlagworte:	Actins - metabolism Albuminuria - metabolism Albuminuria - prevention & control Animals Antioxidants - pharmacology Collagen Type IV - metabolism Creatinine - blood Diabetes Diabetes Mellitus, Experimental - drug therapy Diabetes Mellitus, Experimental - genetics Diabetes Mellitus, Experimental - pathology Diabetes Mellitus, Experimental - physiopathology Diabetic Nephropathies - genetics Diabetic Nephropathies - pathology Diabetic Nephropathies - physiopathology Diabetic Nephropathies - prevention & control Genes Genotype Glomerular Filtration Rate - drug effects Haptoglobins - genetics Haptoglobins - metabolism Hypertrophy Iron - metabolism Kidney - drug effects Kidney - metabolism Kidney - pathology Kidney - physiopathology Kidneys Mice Mice, Inbred C57BL Mice, Transgenic Oxidation Oxidative Stress - drug effects Oxidative Stress - genetics Phenotype Proteins Rodents Studies Vitamin E - pharmacology
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