Thrombin‐mediated activation of A kt signaling contributes to pulmonary vascular remodeling in pulmonary hypertension

Chronic thromboembolic pulmonary hypertension (CTEPH) has been increasingly recognized as a common source of elevated pulmonary vascular resistance and pulmonary hypertension. It is clear that development of pulmonary thromboemboli is the inciting event for this process, yet it remains unclear why s...

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Veröffentlicht in:Physiological reports 2013-12, Vol.1 (7)
Hauptverfasser: Ogawa, Aiko, Firth, Amy L, Ariyasu, Sanae, Yamadori, Ichiro, Matsubara, Hiromi, Song, Shanshan, Fraidenburg, Dustin R, Jason X.‐J. Yuan
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Sprache:eng
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