Mitochondrial permeability transition in the crustacean Artemia franciscana : absence of a calcium-regulated pore in the face of profound calcium storage

When mammalian mitochondria are exposed to high calcium and phosphate, a massive swelling, uncoupling of respiration, and release of cytochrome c occur. These changes are mediated by opening of the mitochondrial permeability transition pore (MPTP). Activation of the MPTP in vivo in response to hypox...

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Veröffentlicht in:	American journal of physiology. Regulatory, integrative and comparative physiology integrative and comparative physiology, 2005-07, Vol.58 (1), p.R68-R76
Hauptverfasser:	MENZE, Michael A, HUTCHINSON, Kirk, LABORDE, Susan M, HAND, Steven C
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Blood gas. Hemoglobin. Myoglobin. Hemotissulary gas exchange. Acid-base balance Calcium Cell metabolism, cell oxidation Cell physiology Crustaceans Fundamental and applied biological sciences. Psychology Molecular and cellular biology Permeability Vertebrates: respiratory system
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