Uteroplacental insufficiency increases apoptosis and alters p53 gene methylation in the full-term IUGR rat kidney
Uteroplacental insufficiency causes intrauterine growth retardation (IUGR), which is associated with adult onset diseases such as hypertension. Previous studies demonstrate that growth retardation in humans and rats decreases glomeruli number; however, the molecular mechanisms responsible for this r...
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Veröffentlicht in: | American journal of physiology. Regulatory, integrative and comparative physiology integrative and comparative physiology, 2003-11, Vol.54 (5), p.R962-R970 |
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