Deficiency of α-sarcoglycan differently affects fast- and slow-twitch skeletal muscles

Alpha-Sarcoglycan (Sgca) is a transmembrane glycoprotein of the dystrophin complex located at skeletal and cardiac muscle sarcolemma. Defects in the alpha-sarcoglycan gene (Sgca) cause the severe human-type 2D limb girdle muscular dystrophy. Because Sgca-null mice develop progressive muscular dystro...

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Veröffentlicht in:	American journal of physiology. Regulatory, integrative and comparative physiology integrative and comparative physiology, 2005-11, Vol.58 (5), p.R1328-R1337
Hauptverfasser:	DANIELI-BETTO, Daniela, ESPOSITO, Alessandra, GERMINARIO, Elena, SANDONA, Dorianna, MARTINELLO, Tiziana, JAKUBIEC-PUKA, Anna, BIRAL, Donatella, BETTO, Romeo
Format:	Artikel
Sprache:	eng
Schlagworte:	Biochemistry Biological and medical sciences Diseases of striated muscles. Neuromuscular diseases Fundamental and applied biological sciences. Psychology Genes Medical sciences Muscular dystrophy Muscular system Neurology Proteins Striated muscle. Tendons Vertebrates: osteoarticular system, musculoskeletal system
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