Effects of maturation, artery size, and chrnoic hypoxia on 5-HT receptor type in ovine cranial arteries
To test the hypothesis that variations in cerebrovascular reactivity to 5-HT among arteries of different size or type, during maturation, or during acclimatization to high altitude involve differences in serotonergic receptor subtype, we determined relative agonist potency orders and antagonist affi...
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| Veröffentlicht in: | American journal of physiology. Regulatory, integrative and comparative physiology integrative and comparative physiology, 1998-09, Vol.44 (3), p.R742 |
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| container_issue | 3 |
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| container_title | American journal of physiology. Regulatory, integrative and comparative physiology |
| container_volume | 44 |
| creator | Teng, Guo Qi Williams, James Zhang, Lubo Purdy, Ralph Pearce, William J |
| description | To test the hypothesis that variations in cerebrovascular reactivity to 5-HT among arteries of different size or type, during maturation, or during acclimatization to high altitude involve differences in serotonergic receptor subtype, we determined relative agonist potency orders and antagonist affinities in common carotid (Com), main branch middle cerebral (Main), and second branch middle cerebral (2BR) arteries from term fetal lambs and nonpregnant adult sheep acclimatized at sea level or at an altitude of 3,820 m for ~110 days. |
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| identifier | ISSN: 0363-6119 |
| ispartof | American journal of physiology. Regulatory, integrative and comparative physiology, 1998-09, Vol.44 (3), p.R742 |
| issn | 0363-6119 1522-1490 |
| language | eng |
| recordid | cdi_proquest_journals_229739665 |
| source | American Physiological Society; EZB-FREE-00999 freely available EZB journals |
| subjects | Blood vessels Brain Sheep |
| title | Effects of maturation, artery size, and chrnoic hypoxia on 5-HT receptor type in ovine cranial arteries |
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