Endogenous estrogen mediates a higher threshold for endotoxin-induced myocardial protection in females

Myocardial endotoxin tolerance may be induced in both males and females; however, it remains unknown whether there are mechanistic and threshold differences between the sexes. We hypothesized that endogenous estrogen mediates a higher threshold for endotoxin (ETX)-induced protection in females. Adul...

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Veröffentlicht in:American journal of physiology. Regulatory, integrative and comparative physiology integrative and comparative physiology, 2006-01, Vol.59 (1), p.R27
Hauptverfasser: Pitcher, Jeffrey M, Wang, Meijing, Tsai, Ben M, Kher, Ajay
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Sprache:eng
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