Effects of ischemia and reperfusion on isolated ventricular myocytes from young adult and aged Fischer 344 rat hearts

1 Department of Pharmacology and 2 Division of Geriatric Medicine, Dalhousie University, Halifax, Nova Scotia, Canada Submitted 16 January 2008 ; accepted in final form 3 March 2008 This study examined the impact of age on contractile function, Ca 2+ homeostasis, and cell viability in isolated myocy...

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Veröffentlicht in:	American journal of physiology. Heart and circulatory physiology 2008-05, Vol.294 (5), p.H2174-H2183
Hauptverfasser:	O'Brien, J. Darcy, Ferguson, Jessica H, Howlett, Susan E
Format:	Artikel
Sprache:	eng
Schlagworte:	Age Factors Aging - metabolism Aging - pathology Animals Calcium - metabolism Calcium Signaling Cardiovascular disease Cell Size Cell Survival Cells Comparative analysis Effects Heart Ventricles - metabolism Homeostasis Isotonic Solutions Male Myocardial Contraction Myocardial Reperfusion Injury - complications Myocardial Reperfusion Injury - metabolism Myocardial Reperfusion Injury - pathology Myocardial Reperfusion Injury - physiopathology Myocardial Stunning - etiology Myocardial Stunning - metabolism Myocardial Stunning - pathology Myocardial Stunning - physiopathology Myocytes, Cardiac - metabolism Myocytes, Cardiac - pathology Rats Rats, Inbred F344 Rodents Studies Time Factors
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