Physiologically based kinetic models for farm animals: Critical review of published models and future perspectives for their use in chemical risk assessment

Physiologically based kinetic (PBK) models in the 10 most common species of farm animals were identified through an extensive literature search. This resulted in 39 PBK models, mostly for pharmaceuticals. The models were critically assessed using the WHO criteria for model evaluation, i.e. 1) purpos...

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Veröffentlicht in:Toxicology in vitro 2019-10, Vol.60, p.61-70
Hauptverfasser: Lautz, L.S., Oldenkamp, R., Dorne, J.L., Ragas, A.M.J.
Format: Artikel
Sprache:eng ; spa
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