Overexpression of Na+/Ca2+ exchanger alters contractility and SR Ca2+ content in adult rat myocytes
The functional consequences of overexpression of rat heart Na+/Ca(2+) exchanger (NCX1) were investigated in adult rat myocytes in primary culture. When maintained under continued electrical field stimulation conditions, cultured adult rat myocytes retained normal contractile function compared with f...
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| Veröffentlicht in: | American journal of physiology. Heart and circulatory physiology 2001-11, Vol.50 (5), p.H2079-H2088 |
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| container_end_page | H2088 |
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| container_issue | 5 |
| container_start_page | H2079 |
| container_title | American journal of physiology. Heart and circulatory physiology |
| container_volume | 50 |
| creator | ZHANG, Xue-Qian JIANLIANG SONG ROTHBLUM, Lawrence I MINGYUE LUN XUJUN WANG FAN DING DUNN, Jeremy LYTTON, Jonathan MCDERMOTT, Paul J CHEUNG, Joseph Y |
| description | The functional consequences of overexpression of rat heart Na+/Ca(2+) exchanger (NCX1) were investigated in adult rat myocytes in primary culture. When maintained under continued electrical field stimulation conditions, cultured adult rat myocytes retained normal contractile function compared with freshly isolated myocytes for at least 48 h. |
| format | Article |
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When maintained under continued electrical field stimulation conditions, cultured adult rat myocytes retained normal contractile function compared with freshly isolated myocytes for at least 48 h.</description><identifier>ISSN: 0363-6135</identifier><identifier>EISSN: 1522-1539</identifier><identifier>CODEN: AJPPDI</identifier><language>eng</language><publisher>Bethesda, MD: American Physiological Society</publisher><subject>Biological and medical sciences ; Calcium ; Fundamental and applied biological sciences. Psychology ; Heart ; Medical imaging ; Neurotransmitters ; Rodents ; Sodium ; Vertebrates: cardiovascular system</subject><ispartof>American journal of physiology. 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Heart and circulatory physiology</title><description>The functional consequences of overexpression of rat heart Na+/Ca(2+) exchanger (NCX1) were investigated in adult rat myocytes in primary culture. When maintained under continued electrical field stimulation conditions, cultured adult rat myocytes retained normal contractile function compared with freshly isolated myocytes for at least 48 h.</description><subject>Biological and medical sciences</subject><subject>Calcium</subject><subject>Fundamental and applied biological sciences. 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| identifier | ISSN: 0363-6135 |
| ispartof | American journal of physiology. Heart and circulatory physiology, 2001-11, Vol.50 (5), p.H2079-H2088 |
| issn | 0363-6135 1522-1539 |
| language | eng |
| recordid | cdi_proquest_journals_229636065 |
| source | American Physiological Society; EZB-FREE-00999 freely available EZB journals |
| subjects | Biological and medical sciences Calcium Fundamental and applied biological sciences. Psychology Heart Medical imaging Neurotransmitters Rodents Sodium Vertebrates: cardiovascular system |
| title | Overexpression of Na+/Ca2+ exchanger alters contractility and SR Ca2+ content in adult rat myocytes |
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