Wortmannin inhibits insulin-stimulated activation of protein phosphatase 1 in rat cardiomyocytes
A major function of insulin in target tissues is the activation of glycogen synthase. Phosphatidylinositol 3-kinase (PI3K) has been implicated in the insulin-induced activation of glycogen synthase, although the true function of this enzyme remains unclear.
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| Veröffentlicht in: | American journal of physiology. Heart and circulatory physiology 1999-05, Vol.45 (5), p.H1520-H1526 |
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| container_end_page | H1526 |
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| container_issue | 5 |
| container_start_page | H1520 |
| container_title | American journal of physiology. Heart and circulatory physiology |
| container_volume | 45 |
| creator | DE LUCA, J. P GARNACHE, A. K RULFS, J MILLER, T. B |
| description | A major function of insulin in target tissues is the activation of glycogen synthase. Phosphatidylinositol 3-kinase (PI3K) has been implicated in the insulin-induced activation of glycogen synthase, although the true function of this enzyme remains unclear. |
| format | Article |
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| fulltext | fulltext |
| identifier | ISSN: 0363-6135 |
| ispartof | American journal of physiology. Heart and circulatory physiology, 1999-05, Vol.45 (5), p.H1520-H1526 |
| issn | 0363-6135 1522-1539 |
| language | eng |
| recordid | cdi_proquest_journals_229629367 |
| source | American Physiological Society; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals |
| subjects | Biochemistry Biological and medical sciences Cardiology Cellular biology Diabetes Fundamental and applied biological sciences. Psychology Heart Insulin Metabolism Vertebrates: cardiovascular system |
| title | Wortmannin inhibits insulin-stimulated activation of protein phosphatase 1 in rat cardiomyocytes |
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