Wortmannin inhibits insulin-stimulated activation of protein phosphatase 1 in rat cardiomyocytes

Wortmannin inhibits insulin-stimulated activation of protein phosphatase 1 in rat cardiomyocytes

A major function of insulin in target tissues is the activation of glycogen synthase. Phosphatidylinositol 3-kinase (PI3K) has been implicated in the insulin-induced activation of glycogen synthase, although the true function of this enzyme remains unclear.

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:American journal of physiology. Heart and circulatory physiology 1999-05, Vol.45 (5), p.H1520-H1526
Hauptverfasser: DE LUCA, J. P, GARNACHE, A. K, RULFS, J, MILLER, T. B
Format: Artikel
Sprache:eng
Schlagworte:
Biochemistry
Biological and medical sciences
Cardiology
Cellular biology
Diabetes
Fundamental and applied biological sciences. Psychology
Heart
Insulin
Metabolism
Vertebrates: cardiovascular system
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:A major function of insulin in target tissues is the activation of glycogen synthase. Phosphatidylinositol 3-kinase (PI3K) has been implicated in the insulin-induced activation of glycogen synthase, although the true function of this enzyme remains unclear.
ISSN:0363-6135
1522-1539