Evidence and consequences of spectrum bias in studies of criteria for liver transplant in paracetamol hepatotoxicity

Objective: In severe paracetamol hepatotoxicity, orthotopic liver transplant (OLT) is a standard treatment in patients judged to have a hopeless prognosis. The most commonly used criteria to make this decision are the King's College Criteria (KCC). We aimed to compare the expected survival for...

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Veröffentlicht in:	QJM : An International Journal of Medicine 2008-09, Vol.101 (9), p.723-729
Hauptverfasser:	Ding, G.K.A., Buckley, N.A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Acetaminophen - poisoning Adult Analgesics, Non-Narcotic - poisoning Biological and medical sciences Evidence-Based Medicine General aspects Humans Liver Failure - chemically induced Liver Failure - mortality Liver Failure - surgery Liver Transplantation - mortality Medical sciences Quality of Life Selection Bias Survival Rate Transplantation, Homologous Treatment Outcome
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