Enhanced calcium cycling and contractile function in transgenic hearts expressing constitutively active G[alpha]^sub o^ protein

In contrast to the other heterotrimeric GTP-binding proteins (G proteins) G... and G..., the functional role of G... is still poorly defined. To investigate the role of Gα... in the heart, we generated transgenic mice with cardiac-specific expression of a constitutively active form of Gα...* (Gα...*...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	American journal of physiology. Heart and circulatory physiology 2008-03, Vol.294 (3), p.H1335
Hauptverfasser:	Zhu, Ming, Gach, Agnieszka A, Liu, GongXin, Xu, Xiaomei, Lim, Chee Chew, Zhang, Julie X, Mao, Lan, Chuprun, Kurt, Koch, Walter J, Liao, Ronglih, Koren, Gideon, Blaxall, Burns C, Mende, Ulrike
Format:	Artikel
Sprache:	eng
Schlagworte:	Calcium Cells Gene expression Glycoproteins Heart Rodents Signal transduction
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!