Protein kinase C-ζ inhibition exerts cardioprotective effects in ischemia-reperfusion injury

Ischemia followed by reperfusion (I/R) in the presence of polymorphonuclear leukocytes (PMNs) results in marked cardiac contractile dysfunction. A cell-permeable PKC-{zeta} peptide inhibitor was used to test the hypothesis that PKC-{zeta} inhibition could attenuate PMN-induced cardiac contractile dy...

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Veröffentlicht in:	American journal of physiology. Heart and circulatory physiology 2005-08, Vol.58 (2), p.H898-H907
Hauptverfasser:	PHILLIPSON, Aisha, PETERMAN, Ellen E, TAORMINA, Philip JR, HARVEY, Margaret, BRUE, Richard J, ATKINSON, Norrell, OMIYI, Didi, CHUKWU, Uchenna, YOUNG, Lindon H
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Cardiology Enzymes Fundamental and applied biological sciences. Psychology Leukocytes Nitric oxide Peptides Vertebrates: cardiovascular system
Online-Zugang:	Volltext
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