Moderate endurance training prevents doxorubicin-induced in vivo mitochondriopathy and reduces the development of cardiac apoptosis

The objective of this work was to test the hypothesis that endurance training may be protective against in vivo doxorubicin (DOX)-induced cardiomyopathy through mitochondria-mediated mechanisms. Forty adult (6-8 wk old) male Wistar rats were randomly divided into four groups (n = 10/group): nontrain...

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Veröffentlicht in:American journal of physiology. Heart and circulatory physiology 2005-08, Vol.58 (2), p.H722-H731
Hauptverfasser: ASCENSAO, Antonio, MAGALHAES, José, SOARES, José M. C, FERREIRA, Rita, NEUPARTH, Maria J, MARQUES, Franklim, OLIVEIRA, Paulo J, DUARTE, José A
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Sprache:eng
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