Detection of the Health Foods Indicating the Estrogen Activity

The use of the health foods has been increasing, and therefore their safety has become an important issue. In recent years, health foods thought to have estrogen activity have appeared on the Japanese market, but no method for detecting the estrogen activity of such foods has been available. The pre...

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Veröffentlicht in:Nihon Eiyō, Shokuryō Gakkai shi 2019, Vol.72(4), pp.159-163
Hauptverfasser: Yamauchi, Jun, Kogure, Sarasa, Horiguchi, Toshihide, Yonezawa, Kayo, Tanioka, Yuri, Furusho, Tadasu, Takebayashi, Jun, Tousen, Yuko, Ishimi, Yoshiko
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container_issue 4
container_start_page 159
container_title Nihon Eiyō, Shokuryō Gakkai shi
container_volume 72
creator Yamauchi, Jun
Kogure, Sarasa
Horiguchi, Toshihide
Yonezawa, Kayo
Tanioka, Yuri
Furusho, Tadasu
Takebayashi, Jun
Tousen, Yuko
Ishimi, Yoshiko
description The use of the health foods has been increasing, and therefore their safety has become an important issue. In recent years, health foods thought to have estrogen activity have appeared on the Japanese market, but no method for detecting the estrogen activity of such foods has been available. The present study assessed whether a “Dual-Luciferase Reporter Assay” (luciferase reporter assay) was useful for detection of estrogen activity in health foods. Food showing high estrogen activity in the luciferase reporter assay had high activity in the uterus growth assay using laboratory animals. It is suggested that the luciferase reporter assay could be an effective technique for detection of estrogen activity in health foods.
doi_str_mv 10.4327/jsnfs.72.159
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subjects Assaying
Dual-Luciferase Reporter Assay
estrogen activity
Estrogens
Food
Food availability
health foods
Laboratory animals
Mammals
Menopause
Natural & organic foods
Uterus
title Detection of the Health Foods Indicating the Estrogen Activity
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