Effectiveness of FK506 on lipid peroxidation in the spinal cord following experimental traumatic injury

An in vivo study in Wistar albino rats with injured spinal cord. Department of Neurosurgery, Biochemistry and Pathology, Gazi University, Ankara, Turkey. The aim of this study was to investigate and compare the effects of FK506 an immunosupressive agent with methylprednisolone (MP) on lipid peroxida...

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Veröffentlicht in:	Spinal cord 2005-01, Vol.43 (1), p.22-26
Hauptverfasser:	KAYMAZ, Memduh, EMMEZ, Hakan, BUKAN, Neslihan, DURSUN, Ayse, KURT, Gökhan, PASAOGLU, Hatice, PASAOGLU, Aydin
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Cerebrospinal fluid. Meninges. Spinal cord Chemotaxis, Leukocyte - drug effects Chemotaxis, Leukocyte - physiology Degenerative and inherited degenerative diseases of the nervous system. Leukodystrophies. Prion diseases Disease Models, Animal Down-Regulation - drug effects Down-Regulation - physiology Drug Synergism Drug Therapy, Combination Edema - pathology Edema - physiopathology Edema - prevention & control Free Radicals - antagonists & inhibitors Free Radicals - metabolism Immunosuppressive Agents - pharmacology Immunosuppressive Agents - therapeutic use Injuries of the nervous system and the skull. Diseases due to physical agents Lipid Peroxidation - drug effects Lipid Peroxidation - physiology Male Malondialdehyde - metabolism Medical sciences Methylprednisolone - pharmacology Methylprednisolone - therapeutic use Nerve Degeneration - pathology Nerve Degeneration - physiopathology Nerve Degeneration - prevention & control Nervous system (semeiology, syndromes) Neurology Oxidative Stress - drug effects Oxidative Stress - physiology Rats Rats, Wistar Spinal Cord - drug effects Spinal Cord - pathology Spinal Cord - physiopathology Spinal Cord Injuries - drug therapy Spinal Cord Injuries - metabolism Spinal Cord Injuries - physiopathology Tacrolimus - pharmacology Tacrolimus - therapeutic use Traumas. Diseases due to physical agents
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