Segment-specific and direction-dependent transport of cadmium and manganese in immortalized S1, S2, and S3 cells derived from mouse kidney proximal tubules

The kidney proximal tubule is a target of many renal toxicants, including cadmium (Cd), and also a place of reabsorption of essential metals in glomerular filtrate to systemic circulation. Although the mechanisms of metal transport in the convoluted proximal tubule (S1 and S2 segments) and the strai...

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Veröffentlicht in:Journal of toxicological sciences 2019, Vol.44(9), pp.611-619
Hauptverfasser: Fujishiro, Hitomi, Hamao, Satoko, Isawa, Misaki, Himeno, Seiichiro
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Sprache:eng
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