TRIM 8 regulates stemness in glioblastoma through PIAS 3‐ STAT 3

Glioblastoma ( GBM ) is the most malignant form of primary brain tumor, and GBM stem‐like cells ( GSC s) contribute to the rapid growth, therapeutic resistance, and clinical recurrence of these fatal tumors. STAT 3 signaling supports the maintenance and proliferation of GSC s, yet regulatory mechani...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Molecular oncology 2017-03, Vol.11 (3), p.280-294
Hauptverfasser:	Zhang, Changming, Mukherjee, Subhas, Tucker‐Burden, Carol, Ross, James L., Chau, Monica J., Kong, Jun, Brat, Daniel J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Angiogenesis Brain cancer Brain stem Brain tumors Cancer therapies Cell growth Cell self-renewal Clonal deletion Gene deletion Gene expression Genotype & phenotype Glioblastoma Kinases Myc protein Nestin Proteasomes Proteins Stat3 protein Stem cells Ubiquitination
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!