Exploring the mechanisms of action of human secretory RN ase 3 and RN ase 7 against Candida albicans

Human antimicrobial RN ases, which belong to the vertebrate RN ase A superfamily and are secreted upon infection, display a wide spectrum of antipathogen activities. In this work, we examined the antifungal activity of the eosinophil RN ase 3 and the skin‐derived RN ase 7, two proteins expressed by...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	MicrobiologyOpen (Weinheim) 2016-10, Vol.5 (5), p.830-845
Hauptverfasser:	Salazar, Vivian A., Arranz‐Trullén, Javier, Navarro, Susanna, Blanco, Jose A., Sánchez, Daniel, Moussaoui, Mohammed, Boix, Ester
Format:	Artikel
Sprache:	eng
Schlagworte:	Ablation Anchoring Antifungal activity Antiinfectives and antibacterials Antimicrobial agents Bacterial infections Candida albicans Cell viability Confocal microscopy Destabilization Drug development E coli Enzymatic activity Fungal infections Fungicides Immunosuppressive agents Infections Leukocytes (eosinophilic) Microscopy Model testing Multitasking Pathogens Peptides Protein expression Proteins Ribonuclease 7 Ribonucleic acid RNA Site-directed mutagenesis Skin Vertebrates Yeast Yeasts
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!