Prostaglandin E 2 promotes MYCN non‐amplified neuroblastoma cell survival via β‐catenin stabilization

Amplification of MYCN is the most well‐known prognostic marker of neuroblastoma risk classification, but still is only observed in 25% of cases. Recent evidence points to the cyclic adenosine monophosphate ( cAMP ) elevating ligand prostaglandin E 2 ( PGE 2 ) and β‐catenin as two novel players in ne...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Journal of cellular and molecular medicine 2015-01, Vol.19 (1), p.210-226
Hauptverfasser:	Jansen, Sepp R., Holman, Rian, Hedemann, Ilja, Frankes, Ewoud, Elzinga, Carolina R. S., Timens, Wim, Gosens, Reinoud, de Bont, Eveline S., Schmidt, Martina
Format:	Artikel
Sprache:	eng
Schlagworte:	Apoptosis Catenin Cell culture Cell cycle Cell lines Cell survival Cell viability COX-2 inhibitors Cyclic AMP Data collection Ectopic expression Forskolin Glucose Glycogen Glycogen synthase kinase 3 Inhibition Kinases Medical prognosis Metastasis Neuroblastoma Nuclear transport Phosphorylation Prostaglandin E Prostaglandin E2 Prostaglandin endoperoxide synthase Protein kinase A Software Stabilization Transcription Translocation Tumors
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!