Ameliorative effect of acetylshikonin on ovalbumin (OVA)‐induced allergic rhinitis in mice through the inhibition of Th2 cytokine production and mast cell histamine release

Acetylshikonin has long been known as an anti‐inflammatory and antioxidative reagent. However, the anti‐allergic effect has not been studied. The aim of this study was to evaluate the effect of acetylshikonin on allergic rhinitis (AR) in mice. Mice were sensitized by intraperitoneal injection of OVA...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	APMIS : acta pathologica, microbiologica et immunologica Scandinavica microbiologica et immunologica Scandinavica, 2019-10, Vol.127 (10), p.688-695
Hauptverfasser:	Fan, Xi‐Hui, Cheng, Lei, Yan, Ai‐Hui
Format:	Artikel
Sprache:	eng
Schlagworte:	Acetylshikonin Administration, Oral Allergens - administration & dosage Allergic rhinitis Aluminum Aluminum hydroxide Animals Anthraquinones - administration & dosage cytokine Cytokines Cytokines - antagonists & inhibitors Disease Models, Animal Enzyme-linked immunosorbent assay Helper cells Histamine Histamine Release - drug effects Hyperplasia Hypersensitivity IL‐4 Immunoglobulin E Immunoglobulin G Immunologic Factors - administration & dosage Inflammation Injections, Intraperitoneal Interferon Interleukins Lymphocytes T Mast Cells - drug effects Mice Nose Oral administration Ovalbumin Ovalbumin - administration & dosage Reagents Rhinitis Rhinitis, Allergic - chemically induced Rhinitis, Allergic - drug therapy Rhinitis, Allergic - pathology Th2 Cells - drug effects Treatment Outcome Tumor necrosis factor
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!