Safety and efficacy of Cerebrolysin in acute brain injury and neurorecovery: CAPTAIN I—a randomized, placebo-controlled, double-blind, Asian-Pacific trial

Objective To evaluate the safety and efficacy of Cerebrolysin as an add-on therapy to local standard treatment protocol in patients after moderate-to-severe traumatic brain injury. Methods The patients received the study medication in addition to standard care (50 mL of Cerebrolysin or physiological...

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Veröffentlicht in:	Neurological sciences 2020-02, Vol.41 (2), p.281-293
Hauptverfasser:	Poon, W., Matula, C., Vos, P. E., Muresanu, D. F., von Steinbüchel, N., von Wild, K., Hömberg, V., Wang, E., Lee, T. M. C., Strilciuc, S., Vester, J. C.
Format:	Artikel
Sprache:	eng
Schlagworte:	Acute Disease Adult Amino Acids - administration & dosage Amino Acids - adverse effects Amino Acids - pharmacology Asia, Southeastern Brain Injuries, Traumatic - complications Brain Injuries, Traumatic - drug therapy Cognitive Dysfunction - drug therapy Cognitive Dysfunction - etiology Double-Blind Method Double-blind studies Far East Female Humans Male Medicine Medicine & Public Health Middle Aged Neurology Neuroprotective Agents - administration & dosage Neuroprotective Agents - adverse effects Neuroprotective Agents - pharmacology Neuroradiology Neurosciences Neurosurgery Original Article Outcome Assessment, Health Care Psychiatry Safety Severity of Illness Index Statistical analysis Traumatic brain injury Young Adult
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