Neurobehavioral profiles of neonates exposed to cocaine prenatally
This study examined the effects of maternal cocaine use on performance on the Neonatal Behavioral Assessment Scale (NBAS). Cocaine-exposed newborns (n = 56) were compared with a non-cocaine-exposed group (n = 30) born to mothers with similar sociodemographic characteristics. Cocaine-exposed newborns...
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Veröffentlicht in: | Pediatrics (Evanston) 1993-04, Vol.91 (4), p.778-783 |
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creator | MAYES, L. C GRANGER, R. H FRANK, M. A SCHOTTENFELD, R BORNSTEIN, M. H |
description | This study examined the effects of maternal cocaine use on performance on the Neonatal Behavioral Assessment Scale (NBAS). Cocaine-exposed newborns (n = 56) were compared with a non-cocaine-exposed group (n = 30) born to mothers with similar sociodemographic characteristics. Cocaine-exposed newborns showed significant reduction in birth weight but did not experience greater obstetric or postnatal complications. On neurobehavioral assessments using the NBAS, cocaine-exposed newborns showed significantly depressed performance on the habituation cluster but not on other NBAS clusters when differences in birth weight were controlled. In a sample of 30 cocaine-exposed newborns matched on birth weight, gestational age, and race to the 30 non-cocaine-exposed newborns, cocaine-exposed newborns continued to show depressed habituation performance. The significance of a selective effect of cocaine exposure on early habituation performance is discussed in terms of the implications for attentional regulation in the first year of life. |
doi_str_mv | 10.1542/peds.91.4.778 |
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In a sample of 30 cocaine-exposed newborns matched on birth weight, gestational age, and race to the 30 non-cocaine-exposed newborns, cocaine-exposed newborns continued to show depressed habituation performance. The significance of a selective effect of cocaine exposure on early habituation performance is discussed in terms of the implications for attentional regulation in the first year of life.</description><identifier>ISSN: 0031-4005</identifier><identifier>EISSN: 1098-4275</identifier><identifier>DOI: 10.1542/peds.91.4.778</identifier><identifier>PMID: 8464666</identifier><identifier>CODEN: PEDIAU</identifier><language>eng</language><publisher>Elk Grove Village, IL: American Academy of Pediatrics</publisher><subject>Adult ; Babies ; Biological and medical sciences ; Birth defects ; Case-Control Studies ; Children ; Children of drug addicts ; Cocaine ; Cocaine - adverse effects ; Delivery. Postpartum. Lactation ; Development ; Drug abusers ; Female ; Gynecology. Andrology. 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On neurobehavioral assessments using the NBAS, cocaine-exposed newborns showed significantly depressed performance on the habituation cluster but not on other NBAS clusters when differences in birth weight were controlled. In a sample of 30 cocaine-exposed newborns matched on birth weight, gestational age, and race to the 30 non-cocaine-exposed newborns, cocaine-exposed newborns continued to show depressed habituation performance. The significance of a selective effect of cocaine exposure on early habituation performance is discussed in terms of the implications for attentional regulation in the first year of life.</description><subject>Adult</subject><subject>Babies</subject><subject>Biological and medical sciences</subject><subject>Birth defects</subject><subject>Case-Control Studies</subject><subject>Children</subject><subject>Children of drug addicts</subject><subject>Cocaine</subject><subject>Cocaine - adverse effects</subject><subject>Delivery. Postpartum. Lactation</subject><subject>Development</subject><subject>Drug abusers</subject><subject>Female</subject><subject>Gynecology. Andrology. 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subjects | Adult Babies Biological and medical sciences Birth defects Case-Control Studies Children Children of drug addicts Cocaine Cocaine - adverse effects Delivery. Postpartum. Lactation Development Drug abusers Female Gynecology. Andrology. Obstetrics Habituation, Psychophysiologic - drug effects Humans Infant development Infant, Newborn - psychology Infants (Newborn) Male Maternal, fetal and perinatal monitoring Medical research Medical sciences Newborn infants Pediatrics Physiological aspects Pregnancy Prenatal Exposure Delayed Effects |
title | Neurobehavioral profiles of neonates exposed to cocaine prenatally |
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